Practical manganese-catalysed highly enantioselective cis-dihydroxylation of electron-deficient alkenes and detection of a cis-dioxomanganese(V) intermediate by high resolution ESI-MS analysis.

نویسندگان

  • Toby Wai-Shan Chow
  • Yungen Liu
  • Chi-Ming Che
چکیده

A practical protocol has been developed for asymmetric cis-dihydroxylation of electron-deficient alkenes with Oxone catalysed by a manganese complex bearing a chiral tetradentate N(4)-donor ligand affording cis-diols in up to 95% yield with up to 96% ee. Analysis of the reaction mixture by high resolution ESI-MS revealed the formation of a cis-dioxomanganese(V) intermediate.

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عنوان ژورنال:
  • Chemical communications

دوره 47 40  شماره 

صفحات  -

تاریخ انتشار 2011